Echinoderms possess a unique connective tissue (Mutable Collagenous Tissue, MCT). Echinoderm MCT is composed by collagen fibrils interconnected by glycosaminoglycans, the major components of neodermis, creating the optimal environment for collagen biosynthesis, showing improved biocompatibility, biodegradability and safety. Echinoderm MCT unique physical, chemical and biological properties allow fabrication of stable hydrogels thorough fibrogenesis. It also constitutes a suitable polymeric matrix for electrospinning, 3D-bioprinting and biocompatible nanocoatings and cell culture R&D projects.
- Cosmetic and nutritional supplements
- Electrospinning and 3D-Bioprinting
- Cell culture and tissue engineering
- Biomaterials and nanotechnology
To ensure lot-to-lot consistency, this produce is tested by SDS-PAGE, HYP content, amino acid profile and FTIR to conform to characteristics of a standard reference collagen type-I (Human, Bovine and Rat Tail). Purity and retention of native helical structure was controlled by SDS-PAGE gel electrophoresis.
Echinoderm Type-I Collagen constitutes an ideal standard for collagen purity (>98% collagen content), functionality, and one of the most native-like collagen available as of today.
Protein Molecular Weight: 150 – 300 kDa.
Conformation: Triple-helix of beta and two alpha[2(l)and 1(1)] chains.
Tissue Specificity: Echinoderm Mutable Collagenous Tissue (MCT), echinoerm mutable collagenous tissue (MCT), composed by collagen fibrils interconnected by glycosaminoglycans, creating a suitable environment for collagen biosynthesis and cell growth.