Seallagen (Echinoderm Type I Collagen-Solution) constitutes an ideal standard for collagen purity (>98% collagen content), functionality, and one of the most native-like collagen available as of today. Isolated from echinoderm mutable collagenous tissue (MCT) known by its unique collagen composition, Seallagen shows excellent biocompatibility and safety, due to key biological properties, such as biodegradability and low antigenicity, eliminating the risk of serious disease transmission. Marine Essence Biosciences manufacturing processes comply with stringent quality standards that have proven to yield unsurpassed lot-to-lot consistency.
- Type I Collagen Standard
- Antigen for Antibody Production
- Coating Material for Cell Culture and Medical Devices
- Formation of Collagen Gels and Bioinks
- Fabrication of Biomaterials and Medical Devices
To ensure lot-to-lot consistency, this produce is tested by SDS-PAGE, HYP content, amino acid profile and FTIR to conform to characteristics of a standard reference collagen type-I (Human, Bovine and Rat Tail). Purity and retention of native helical structure was controlled by SDS-PAGE gel electrophoresis.
Purity analysis by native gel electrophoresis and infrared spectroscopy, showing repeatability batch-to-batch in product quality. ME-Bio MCT production batches 1 to 7. Std: Bovine collagen type-I standard (PureCol, Advanced Biomatrix). Inserted reference FTIR for type-I collagen
Echinoderm Type-I Collagen constitutes an ideal standard for collagen purity (>98% collagen content), functionality, and one of the most native-like collagen available as of today.
|Natural Extra Cellular Matrix
Mutable collagenous tissue is a unique natural extracellular matrix composed by collagen and glycosaminoglycan, the major components of neodermis, creating the optimal environment for new collagen biosynthesis and promoting integrin binding.
Safe Source of Collagen
Gene Symbol : COL1A1
Protein Molecular Weight: 150 – 300 kDa.
Conformation : Triple-helix of beta and two alpha chain (Alpha Chain Sequence COL1A2).
Tissue Specificity : Echinoderm Mutable Collagenous Tissue (MCT).
Function : Type I collagen belongs to the fibrillar forming collagen group.
Storage & Handling
- 2 to 8 ℃. Refer to SDS. Safety Data Sheet